Meta-Analysis and Systematic Reviews --- providing the highest level of evidence of interventions, this type of work is extremely time consuming and not really rewarding, and you better don't calculate reward/hour of work. Despite they gain more and more reputation in the medical decision world, the "problem" is they regularly show that an acknowledged and widely used intervention (and which may profit to several parties/industry etc) is not that beneficial, or benefit only under certain circumstances (which may need further research). And to make the connection to what I wrote under 4., the fear is that an intervention that is beneficial under certain circumstances, might be completely retrieved (from reimbursement for example).

Source author: Katharina Beyer katharina.beyer@etu.unige.ch